Front Oncol 2019;9:749. Early research suggests that astragalus, given intravenously (by IV) or taken by. Heres how much is safe to take. Herald of Medicine 2003;22(8):556-557. Zhong.Nan.Da.Xue.Xue.Bao.Yi.Xue.Ban. Astragalus is a powerful "non-specific" immune modulator. Anti-diabetic activity of herbal drugs. Lishizhen Medicine and Materia Medica Research 2007;18:1743-1744. Liu, J. P., Yang, M., and Du, X. M. Herbal medicines for viral myocarditis. Astragalus has been found to interact with certain medications used to suppress immune function, according to the NCCIH. Astragalus, also known as hung q or milkvetch, is most commonly known for its use in traditional Chinese medicine (1, 2). Li, S. Q., Yuan, R. X., and Gao, H. [Clinical observation on the treatment of ischemic heart disease with Astragalus membranaceus]. 2003;10(5):1507-1512. Information from this source is evidence-based and objective, and without commercial influence. Preliminary study of traditional Chinese medicine treatment of minimal brain dysfunction: analysis of 100 cases. View abstract. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(4):199-202. View abstract. Fan L. Observation of Chinese and Western medicine for the treatment of 72 cases with congestive heart failure. Chin Med J (Engl) 1998;111:17-23. Z., and Kandolf, R. [Effect and mechanism of Astragalus membranaceus on coxsackie B3 virus RNA in mice]. Astragalus is usually well-tolerated. Astragalus may be safe when used orally and appropriately. View abstract. Here's an in-depth look at how CBD may interact with other substances, including over-the-counter medications and prescription drugs. What were Cardinal Richelieu accomplishments? (5) Helping to maintain healthy cholesterol levels (12) 6. Geng, C. S. [Advances in immuno-pharmacological studies on Astragalus membranaceus]. Fang Z, Qin Y. Cheng L, Zhang G, Zhou Y, Lu X, Zhang F, Ye H, Duan J. Though theres no official consensus on the most effective form or dosage of astragalus, 930 grams per day is typical (38). Taking astragalus along with cyclophosphamide might decrease the effects of cyclophosphamide. View abstract. Zhou, R. F., Liu, P. X., and Tan, M. [Effect of Astragalus mongholicus injection on proliferation and apoptosis of hormone sensitive (MCF-7) breast cancer cell lines with physiological dose E2]. Z., and He, M. X. 2000;20(7):504-507. According to the American Thyroid Association (ATA), taking thyroid medication before bed is also OK, but you should take it at the same time each night. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Journal of Traditional Chinese Medicine 1986;27(4):37-39. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1-27-2011;133(2):412-419. Jin, R., Wan, L. L., Mitsuishi, T., Kodama, K., and Kurashige, S. [Immunomodulative effects of Chinese herbs in mice treated with anti- tumor agent cyclophosphamide]. 2009;29(6):501-505. Xiong, M., He, Q., Lai, H., Huang, W., Wang, L., Yang, C., and Wang, J. Radix Astragali injection enhances recovery from acute acoustic trauma. 2009;29(6):1192-1194. 2006;26(9):625-628. All rights reserved. View abstract. Astragalus membranaceus and Polygonum multiflorum protect rat heart mitochondria against lipid peroxidation. Yan, H. J. 30 cases of infantile viral myocarditis treated by integrated Chinese and western drugs. They experienced greater improvements in heart function compared to those receiving standard treatment alone (15). View abstract. Supplements are available as capsules and liquid extracts. The phase IV clinical study analyzes what interactions people who take Nac and Astragalus have. Do not take astragalus root for more than seven consecutive days unless your physician instructs otherwise. China Pharmaceuticals 2000;9(7):44. Other types of astragalus, including some that grow in the United States, have different components and could make you sick, according to NCCIH. [The effect of herbal medicine including astragalus membranaceus (fisch) bge, codonpsis pilosula and glycyrrhiza uralensis fisch on airway responsiveness]. J Nat.Med 2009;63(4):421-429. Ma Z, Cheng X Wang L. Huangqi injection as the assisted treatment for 86 cases with chronic pulmonary heart failure. Thromb.Haemost. Pilot randomized controlled trial of Chinese herbal treatment for HIV- associated symptoms. Zhang L, Wang G Zhang G. Therapeutic effect observation of Huangqi injection as assisted treatment for pulmonary heart failure. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Clin Lab Immunol 1988;25:119-23. Speak to your doctor before taking astragalus supplements if you are taking other herbal medications or treatments. If you want to take astragalus, make sure you know what time of day to take it for the best results! 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. Claudia received her MS in Nutrition from the University of Tennessee Knoxville in 2010. J Tradit.Chin Med 1986;6(3):187-190. Cochrane.Database.Syst.Rev. Be cautious of taking astragalus supplements if you have allergies to certain medications or foods. Chao, M., Zou, D., Zhang, Y., Chen, Y., Wang, M., Wu, H., Ning, G., and Wang, W. Improving insulin resistance with traditional Chinese medicine in type 2 diabetic patients. View abstract. View abstract. Clinical observation of Astragalus injection for 30 cases with congestive heart failure. Jiangbo, Z., Xuying, W., Yuping, Z., Xili, M., Yiwen, Z., and Tianbao, Z. View abstract. Zhongguo Zhong.Yao Za Zhi. 2008;28(6):495-498. Yao, X. J., Wainberg, M. A., and Parniak, M. A. Yin J, Wei Q. Chin Med J (Engl) 1990;103:14-8. Gently dig the base of the stem to reveal the taproot. Clinical research on treatment of acute viral myocarditis by Astragalactoside injection [in Chinese]. Firenzuoli, F., Gori, L., Di Simone, L., and Morsuillo, M. Important bias in the Astragalus meta-analysis. One clinical study found that taking astragalus twice daily may reduce symptoms like sneezing and runny nose in people with allergies.. Traditional Chinese medicine holds that children with a fever should not take astragalus because it may increase the fever and result in it lasting longer. It is created by eHealthMe based on reports of 5 people who take the same drugs from the FDA, and is updated regularly. Zhejiang J TCM 1994;29:487-488. Zeng, F. The effect of Astragalus injection on incipient diabetic nephropathy and plasma endothelin. 2006;26(6):552-554. In the United States, astragalus, an immune stimulant, is taken to prevent the common cold and upper respiratory infections. This green powder is made with organic veggies that also helps to provide the energy that you need to get through the day and it is filled with adaptogens as well. Zhou Y, Yu, X. H., and Yang, Y. H. Observation of astragaloside on treating viral myocarditis in 40 cases [in Chinese]. Traditional Chinese Drug Research & Clinical Pharmacology 1998;9(2):80-81. Phytother.Res 2003;17(9):1016-1020. View abstract. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Huanqi the treatment of viral myocarditis caused by the clinical research of arrhythmia. Scand J Clin Lab Invest 1997;57:521-7. Take 3 capsules twice daily. 1994;14(11):664-666. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Nan.Fang Yi.Ke.Da.Xue.Xue.Bao. View abstract. 2009;29(7):1402-1404. Qin L. Therapeutic effect observation of Chinese and western medicine in the treatment of congestive heart failure. Astragalus is an herbal supplement that has been used for centuries in traditional Chinese medicine. Additionally, one clinical study showed that 500 mg of astragalus by IV three times weekly may improve the extreme tiredness associated with chemotherapy. View abstract. J Ethnopharmacol. A., and Abrams, D. I. Well tell you about how they work, which ones to take, and pitfalls to avoid. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. J Altern.Complement Med 2010;16(4):375-395. The effect of Astragalus on early stage of diabetic nephropathy. Shen, P., Liu, M. H., Ng, T. Y., Chan, Y. H., and Yong, E. L. Differential effects of isoflavones, from Astragalus membranaceus and Pueraria thomsonii, on the activation of PPARalpha, PPARgamma, and adipocyte differentiation in vitro. Chen, M. L., Liu, W. J., Wang, C. Y., Zhu, X. M., Yin, J. F., Wang, D. X., and Liu, P. [Effects of yishenjiangyafang on blood pressure and protecting renal function in RPH rats]. Guo, Q., Peng, T. Q., and Yang, Y. Zhou Z, Cai A Luo C Zeng X. However, more studies are needed to confirm this effect (31). The amount of astaxanthin found in whole food sources is generally safe and can be consumed with minimal risk of side effects. Su, L., Mao, J. C., and Gu, J. H. [Effect of intravenous drip infusion of cyclophosphamide with high-dose Astragalus injection in treating lupus nephritis]. Jiao X, Duan Y. J Pharm Pharmacol 2003;55:1275-82. Chin J Indigenous Med 1997;3(3):21-22. 3-28-2008;116(3):413-421. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(5):268-70, 259. Though no dosage recommendation exists, up to 60 grams daily for up to four months appears to be safe for most people. Zhongguo Wei Zhong.Bing.Ji.Jiu.Yi.Xue. Liu, Z. G., Xiong, Z. M., and Yu, X. Y. J Int Soc Sports Nutr 2021;18(1):57. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. By subscribing you agree to the Terms of Use and Privacy Policy. [Extracorporeal experimental study on immuno-modulatory activity of Astragalus memhranaceus extract]. He, Z. P., Wang, D. Z., Shi, L. Y., and Wang, Z. Q. 2005;25(5):400-403. Astragalus is becoming more common in skincare products such as creams and serums, and there is some very preliminary research to show that it may protect skin against photoaging, or skin damage from sunlight and UV rays. View abstract. Immune restoration and/or augmentation of local graft versus host reaction by traditional Chinese medicinal herbs. View abstract. Zhai L, Wang M Yue J Ma Y. Sichuan Journal of Physiological Sciences 2006;28(2):81. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. View abstract. Academic Proceedings of National Emergency Medicine Conference on Serious Disease 2005;156-157. 1996-2023 Everyday Health, Inc., a Ziff Davis company. 2003;90(5):904-914. Yang, Y. Li, M., Wang, W., Xue, J., Gu, Y., and Lin, S. Meta-analysis of the clinical value of Astragalus membranaceus in diabetic nephropathy. Yang H, Kang X. 2004;24(7):593-595. 2003;23(10):733-735. Cochrane Database Syst.Rev. Li, L. Diabetic nephropathy treating with Astragalus. 2005 - 2023 WebMD LLC. Xu F, Zhang Y, Xiao S, et al. People sometimes use it on the skin for wound care. Appl J Gen Pract 2008;3:234-235. Zhejiang JLTCWM 2005;15(1):32. Neurochem.Res 2010;35(1):33-41. You should take astragalus root preparations with a full glass of water. In rare cases, taking Astragalus by mouth can cause rashes, itchy skin, nasal problems or stomach discomfort. View abstract. For professional medical information on natural medicines, see Natural Medicines Comprehensive Database Professional Version. A Detailed Beginners Guide. Zhang HE and et al. Chen, H. and Weng, L. [Comparison on efficacy in treating liver fibrosis of chronic hepatitis B between Astragalus Polygonum anti-fibrosis decoction and jinshuibao capsule]. 1992;12(11):669-71, 645. Zhang, L. Wang Y. J. Wang G. Z. Li S, Hao J Wu F et al. Astragalus is also classified as an adaptogen which means it helps the body deal with and adapt to stress. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. Dong, J., Gu, H. L., Ma, C. T., Zhang, F., Chen, Z., and Zhang, Y. Check that the supplement has been verified by a third party or a regulatory organization like US Pharmacopeia (USP) or NSF International. Dig and twist until a good portion of the root comes out. [Experimental study of the effect of Astragalus membranaceus against herpes simplex virus type 1]. View abstract. If youve never heard of astragalus, there are a lot of great reasons why you should take it, mainly because it can help support your immune system. Some medical professionals argue against taking herbal supplements for kidney disease, including astragalus supplements. View abstract. Always discuss the use of supplements with your healthcare provider first. Astragalus is believed to prolong life and used to treat a wide variety of ailments, such as fatigue, allergies and the common cold. View abstract. 2003;28(1):78-80. Liang, H. Y., Hou, F., Ding, Y. L., Zhang, W. N., Huang, X. H., Zhang, B. Y., and Liu, Y. Zhang J, Jia L Du Y. J Clin Oncol 7-1-2006;24(19):3215-3216. The curative effect of the treatment of chronic congestive cardiac deficiency by Astragalue injection and digoxin. Zou, Y. H. and Liu, X. M. [Effect of astragalus injection combined with chemotherapy on quality of life in patients with advanced non-small cell lung cancer]. Gao Z, Zhang L Xu Y Liu L Zhang L. Clinical observation of Astragalus injection for congestive heart failure. Liu, J., Liang, P., Yin, C., Wang, T., Li, H., Li, Y., and Ye, Z. Are there any side effects to taking astragalus root? Zhang, J. G., Yang, N., and He, H. [Effect of astraglus injection on serum apoptosis relevant factors in patients with chronic heart failure]. View abstract. Zhong Guo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2008;28(5):467-469. Most widely known as astragalus (aka. Auyeung, K. K., Law, P. C., and Ko, J. K. Astragalus saponins induce apoptosis via an ERK-independent NF-kappaB signaling pathway in the human hepatocellular HepG2 cell line. Wang, Q. L. Application of Astragalus injection on 30 patients with diabetic nephropathy. Sara Nuss is a University of Pittsburgh alumna with a passion for writing and journalism. Astragalus. Zhang, W. J., Hufnagl, P., Binder, B. R., and Wojta, J. Antiinflammatory activity of astragaloside IV is mediated by inhibition of NF-kappaB activation and adhesion molecule expression. Journal of Practical Traditional Chinese Medicine 2008;24(3):164-165. Zhong.Xi.Yi.Jie.He.Za Zhi. Chen, P. Y., Zhou, F., Chen, W. L., Ceng, Y., and Luo, L. Y. 2013 Feb;20(2):223-31. Clinical observation of Huangqi injection for the treatment of pulmonary heart disease refractory heart failure. Yang, Q. Y., Lu, S., and Sun, H. R. Clinical effect of Astragalus granule of different dosages on quality of life in patients with chronic heart failure. Batey RG, Bensoussan A, Fan YY, and et al. Wong, E. L., Sung, R. Y., Leung, T. F., Wong, Y. O., Li, A. M., Cheung, K. L., Wong, C. K., Fok, T. F., and Leung, P. C. Randomized, double-blind, placebo-controlled trial of herbal therapy for children with asthma. By clicking Subscribe, I agree to the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Smoking Pot Every Day Linked to Heart Risks, Artificial Sweetener Linked to Heart Risks, FDA Authorizes First At-Home Test for COVID and Flu, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox, Becoming a Vegetarian: Foods to Choose From. View abstract. View abstract. Effect of Astragulas membranaceus on natural killer cell activity and induction of alpha- and gamma- interferon in patients with coxsackie B viral myocarditis. Astragalus root can be found in many different forms. Yang Y. Zhongguo Zhong Xi Yi Jie He Za Zhi 1994;14(3):142-144, 131-2. Its considered an adaptogen. View abstract. They contribute to your overall wellbeing and can be added to food, mixed into beverages or taken as tinctures (liquid concentrates) or supplements. (11) Astragalus supports "oxygen uptake and the systemic utility of oxygen.". 550. But testing doesnt prove that a product is safe or effective. Liaoning Journal of Practical Diabetes 2002;10:34-35. The University of Maryland Medical Center states that the pediatric dosage is calculated using the standard adult dosage based on a 150-lb.